Winsor McCay, Little Sammy Sneeze, New York Herald, January 7th, 1906

Winsor McCay, Little Sammy Sneeze, New York Herald, Sunday January 7th, 1906

Little Sammy Sneeze was a comic strip by American cartoonist Winsor McCay. In each episode the titular Sammy sneezed himself into an awkward or disastrous predicament. The strip ran from July 24, 1904 until December 9, 1906 in the New York Herald, where McCay was on the staff. It was McCay's first successful comic strip; he followed it with Dream of the Rarebit Fiend later in 1904, and his best-known strip Little Nemo in Slumberland in 1905.

In contrast to the imaginative layouts of Little Nemo, Sammy Sneeze was confined to a rigid grid and followed a strict formula: Sammy's sneeze would build frame by frame, contorting the protagonist's face until it erupted in the second-to-last panel. In the closing panel he suffered the consequences—often a kick in the rear.

McCay's artwork was finely detailed and highly accurate in its persistent repetition. He delved into modernist experimentation, shattering fourth walls and even the strip's panel borders. The panel-by-panel buildup displayed McCay's concern with depicting motion, a concern that was to culminate in his pioneering animated films of the 1910s, such as Gertie the Dinosaur (1914).
(blatantly reiterated from Wikipedia - https://en.wikipedia.org/wiki/Little_Sammy_Sneeze)

This piece has never been presented at auction before now (that I could find). There have been only four others offered over the last 25 years.